Hair loss and seborrheic dermatitis are two of the most common scalp concerns, and they frequently occur together. In response, Korean cosmetic manufacturer Cosmax has developed Dandriome™, a new microbiome-based ingredient that targets both conditions by restoring balance to the scalp environment.

The Link Between Hair Loss and the Scalp Microbiome

Cosmax researchers found that individuals with hair loss showed lower microbial diversity and fewer microbes responsible for acidifying the scalp. This acidification process helps maintain a healthy pH, which is essential for scalp function. The team also identified suppressed lipid metabolism in the same group, which contributes to excess oil production and inflammation.

These findings suggest that an imbalanced scalp microbiome may play a key role in both hair thinning and seborrheic dermatitis, the inflammatory condition behind flaking and irritation.

How Dandriome™ Works

Based on these insights, Cosmax created Dandriome™ by isolating beneficial microorganisms found more frequently in healthy scalps. When applied to the scalp, the ingredient acts on multiple levels:

  • Regulates sebum by suppressing lipid production factors
  • Reduces flaking by inhibiting hyperkeratosis, the thickening of the scalp’s outer layer
  • Targets Malassezia, a yeast overgrowth commonly linked to seborrheic dermatitis
  • Stimulates dermal papilla cells, which are essential for hair follicle activity and growth

This multi-pathway approach makes Dandriome™ one of the first ingredients to simultaneously address the microbial, inflammatory, and follicular aspects of scalp health.

Toward Scalp-First Haircare

Dandriome™ is part of Cosmax’s larger commitment to microbiome-based innovation. The company showcased this ingredient at the International Society of Hair Restoration Surgery (ISHRS) meeting, alongside other research using hair organoids to model male pattern hair loss.

By focusing on the scalp microbiome, Cosmax is helping redefine how we think about hair loss prevention and scalp treatment. For those navigating both thinning hair and persistent irritation, microbiome-focused ingredients like Dandriome™ may offer a more holistic solution.

Sources:

  • Cosmax Introduces Dandriome™: A Microbiome-based Solution To Combat Hair Loss And Seborrheic Dermatitis. The Monodist, 2025.

  • Cosmax ingredient address co-occurrence of hair loss and seborrheic dermatitis. CosmeticsDesign-Asia, April 2025.