Exosome Therapy in NYC

Exosome therapy is an emerging treatment in regenerative aesthetics that uses cell-derived vesicles to promote skin repair, reduce inflammation, and support rejuvenation. Dr. Jane Yoo offers exosome-based protocols designed to support healthy skin function using scientifically-informed approaches and expert guidance.

What are exosomes?

Exosomes are nanoscale extracellular vesicles secreted by nearly all types of cells. They carry biologically active contents including proteins, lipids, and RNA molecules, and act as messengers between cells by transferring these materials to recipient cells. This exchange influences processes such as wound healing, immune response, cell repair, and tissue regeneration.

Although they were once thought to be cellular waste, exosomes are now recognized as key players in cell-to-cell communication, capable of reprogramming recipient cells based on their cargo.

Exosomes differ from stem cells in that they are not living cells, and contain no DNA. Instead, they deliver the functional payloads that stem cells use to influence tissue repair.

How are exosomes used in dermatology?

In aesthetic medicine and dermatology, exosome therapy is being explored for its potential to:

  • Improve post-procedural healing following lasers, microneedling, or RF treatments
  • Stimulate hair growth in individuals with androgenetic alopecia or thinning
  • Reduce signs of photoaging and fine lines
  • Support skin barrier repair and hydration
  • Address post-inflammatory hyperpigmentation and scarring

Exosomes may be applied topically or injected into the skin, depending on the treatment goal and the clinical protocol.

How do exosomes work?

Exosomes interact with target cells through surface proteins and receptors, fuse with the membrane, and release their cargo directly into the recipient cell. Once inside, the proteins, microRNAs, and lipids can influence cellular behaviorby:

  • Regulating gene expression
  • Promoting collagen and elastin synthesis
  • Modulating inflammation and immune activity
  • Enhancing angiogenesis and tissue remodeling

The source and content of exosomes matter. Many formulations used in cosmetic procedures are derived from mesenchymal stem cells (MSCs), chosen for their anti-inflammatory and regenerative properties.

What is the treatment experience like?

Exosome therapy is often paired with energy-based treatments such as microneedling, RF microneedling, or laser resurfacing. When applied topically or injected immediately after these procedures, exosomes can accelerate recovery and enhance outcomes.

Treatment steps typically include:

  • Cleansing and preparation of the skin
  • Performance of the primary procedure (e.g., microneedling)
  • Application or injection of exosomes to the treated areas
  • Minimal downtime, depending on the paired procedure

A series of sessions may be recommended for cumulative benefits.

What are the potential benefits?

Exosome therapy may support:

  • Faster recovery and reduced redness after in-office treatments
  • Improved skin texture, hydration, and glow
  • More even skin tone and reduced hyperpigmentation
  • Enhanced scalp health and visible hair thickening
  • Reduction in the appearance of acne scars or fine lines

While early clinical use is promising, it’s important to note that exosome therapy is still considered investigational, and not yet FDA-approved.

Who is a candidate for exosome therapy?

You may be a good candidate for exosome therapy if you:

  • Are seeking a regenerative boost to your laser or microneedling treatments
  • Have sensitive or post-inflammatory skin in need of barrier repair
  • Are exploring non-surgical approaches to hair thinning
  • Prefer biologically-based, cell-free treatments for skin support

Dr. Yoo will assess your goals and skin condition to determine whether exosome therapy is an appropriate and safe option.

Is exosome therapy safe?

Exosome therapy is generally well tolerated, especially when used topically. However, because it involves biologically active materials, it is important to understand the potential risks. These may include:

  • Temporary redness, swelling, or sensitivity at the application site
  • Allergic reactions or immune responses in rare cases
  • Lack of response depending on individual biology or treatment pairing

Exosomes used in our practice are non-cellular, sterile, and free of DNA. They do not contain live stem cells.

It is important to note that exosome products are not currently FDA-approved, and their clinical use remains investigational. Dr. Yoo provides this treatment under informed consent for patients seeking to explore the regenerative benefits of exosomes.